2022

Persisting Microbiota and Neuronal Imbalance Following T. gondii Infection Reliant on the Infection Route. French T., Steffen J., Glas A., Osbelt L., Strowig T., Schott B.H., Schüler T., Dunay I.R. Front Immunol. 2022 Jul 11;13:920658. https://doi.org/10.3389/fimmu.2022.920658

Choosing memory retrieval strategies: a critical role for inhibition in the dentate gyrus. Albrecht A., Müller I., Weiglein A., Pollali E., Çalışkan G.Stork O. bioRxiv 2022.05.02.490267; https://doi.org/10.1101/2022.05.02.490267

Feedback-related EEG dynamics separately reflect decision parameters, biases, and future choices. Kirschner H., Fischer A.G., Ullsperger M., NeuroImage, Volume 259, 2022, 119437, ISSN 1053-8119, https://doi.org/10.1016/j.neuroimage.2022.119437

Monitoring regional astrocyte diversity by cell-type specific proteomic labeling in vivo. Prabhakar P., Pielot R., Landgraf P., Wissing J., Bayrhammer A., van Ham M., Gundelfinger E.D., Jänsch L., Dieterich D.C.Müller A. bioRxiv 2022.06.07.495069; https://doi.org/10.1101/2022.06.07.495069

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease. Confettura A.D., Cuboni E., Ammar M.R., Jia S., Gomes G.M., Yuanxiang P., Raman R., Li T., Grochowska K.M., Ahrends R., Karpova A., Dityatev A., Kreutz M.R. Transl Neurodegener. 2022 Jan 6;11(1):2. https://doi.org/10.1186/s40035-021-00277-8

Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3. Baidoe-Ansah D., Sakib S., Jia S., Mirzapourdelavar H., Strackeljan L., Fischer A., Aleshin S., Kaushik R., Dityatev A. Cells. 2022 Jun 27;11(13):2033. https://doi.org/10.3390/cells11132033

Brevican and Neurocan Cleavage Products in the Cerebrospinal Fluid – Differential Occurrence in ALS, Epilepsy and Small Vessel Disease. Hußler W., Höhn L., Stolz C., Vielhaber S., Garz C., Schmitt F.C., Gundelfinger E.D., Schreiber S. and Seidenbecher C.I. Front. Cell. Neurosci. 2022 16:838432. https://doi.org/10.3389/fncel.2022.838432

2021

Influenza A Virus (H1N1) Infection Induces Microglial Activation and Temporal Dysbalance in Glutamatergic Synaptic Transmission. Düsedau H.P., Steffen J., Figueiredo C.A., Boehme J.D., Schultz K., Erck C., Korte M., Faber-Zuschratter H., Smalla K.H., Dieterich D., Kröger A., Bruder D., Dunay IR.mBio. 2021 Oct 26;12(5):e0177621. https://doi.org/10.1128/mBio.01776-21

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R. Dankovich T.M., Kaushik R., Olsthoorn L.H.M., Petersen G.C., Giro P.E., Kluever V., Agüi-Gonzalez P., Grewe K., Bao G., Beuermann S., Hadi H.A., Doeren J., Klöppner S., Cooper B.H., Dityatev A., Rizzoli S.O. Nat Commun. 2021 Dec 8;12(1):7129. https://doi.org/10.1038/s41467-021-27462-7

Antibiotic-induced gut dysbiosis leads to activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus. Çalışkan G., French T., Enrile Lacalle S., Del Angel M., Steffen J., Heimesaat MM., Rita Dunay I., Stork O. (2021) Brain, Behavior, and Immunity 99:203-217. https://doi.org/10.1016/j.bbi.2021.10.007

Brain extracellular matrix: An upcoming target in neurological and psychiatric disorders. Dityatev A., Seidenbecher C. and Morawski, M. (2021) Eur J Neurosci 2021 53: 3807-3810. https://doi.org/10.1111/ejn.15336

CSF and PET biomarkers for noradrenergic dysfunction in neurodegenerative diseases: a systematic review and meta-analysis. Lancini E.Haag L., Bartl F., Rühling M., Ashton N.J., Zetterberg H., Düzel E.Hämmerer D.Betts M.J. https://doi.org/10.1101/2021.09.30.21264271

Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice. Strackeljan L., Baczynska E., Cangalaya C., Baidoe-Ansah D., Wlodarczyk, J.; Kaushik R., Dityatev A.  Cells2021, 10, 1862. https://doi.org/10.3390/cells10081862

Transgenic modelling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function. Madencioglu D.A., Çalışkan G., Yuanxiang P., Rehberg K., Demiray Y.E., Kul E., Engler A., Hayani H., Bergado-Acosta J.R., Kummer A., Müller I., Song I., Dityatev A., Kähne T., Kreutz M.R., Stork O. iScience in press, 2021. https://doi.org/10.1016/j.isci.2021.102868

The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling. Annamneedi A., del Angel C.M., Gundelfinger E.D., Stork O., Caliskan G.. International Journal of Molecular Sciences 22(15):7944. 2021. https://doi.org/10.3390/ijms22157944

Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses. Bucher M., Niebling S., Han Y., Molodenskiy D., Hassani Nia F., Kreienkamp H.J., Svergun D., Kim E., Kostyukova A.S., Kreutz M.R., Mikhaylova M. Elife. 202110:e66165. https://doi.org/10.7554/eLife.66165 

Met carriers of the BDNF Val66Met polymorphism show reduced Glx/NAA in the pregenual ACC in two independent cohorts. Martens, L., Herrmann, L., Colic, L., Li, M., Richter, A., Behnisch, G., Stork, O., Seidenbecher, C., Schott, B.H., Walter, M. Sci Rep. 2021 Mar 24;11(1):6742. https://doi.org/10.1038/s41598-021-86220-3

To err is (not only) human: Mechanisms of post-error attentional regulation illuminated in mice. Ullsperger, M., Stork, O. Neuron 109(7):1074-1076. 2021  https://doi.org/10.1016/j.neuron.2021.03.014

Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats. Derbis M, Kul E, Niewiadomska, D., Sekrecki, M., Piasecka, A., Taylor, K., Hukema, R.K., Stork, O., Sobczak, K. Nat Commun. 2021 Feb 24;12(1):1265.PMID: 33627639 https://doi.org/10.1038/s41467-021-21021-w

The nuclear lamina is a hub for the nuclear function of Jacob. Samer, S., Raman, R., Laube, G., Kreutz, M.R., Karpova, A.Mol Brain. 2021 14(1):9. https://doi.org/10.1186/s13041-020-00722-1

Age impairs mnemonic discrimination of objects more than scenes: A web-based, large-scale approach across the lifespan. J. Gusten, G. Ziegler, E.Duzel, D. Berron. Cortex. 2021 Apr 137, 138-148; https://doi.org/10.1016/j.cortex.2020.12.017

Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment. M. Borgmeyer, C. Coman, C. Has, H.F. Schött, T. Li, P. Westhoff, Y.F.H. Cheung, N. Hoffmann, P. Yuanxiang, T. Behnisch, G.M. Gomes, M. Dumenieu, M. Schweizer, M. Chocholoušková, M. Holčapek, M. Mikhaylova, M.R.*Kreutz, R*. Ahrends. Cell Rep 2021 Oct 5; 37(1):109797; https://doi.org10.1016/j.celrep.2021.109797

Feedback-related EEG dynamics separately reflect decision parameters, biases, and future choices. H. Kirschner, A.G. Fischer, M. Ullsperger.bioRxiv  2021 Jun 15,05.10.443374; https://doi.org/10.1101/2021.05.10.443374

2020

Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis. Stoyanov, S., Sun, W., Düsedau, H.P., Cangalaya, C., Choi, I., Mirzapourdelavar, H., Baidoe‐Ansah, D., Kaushik, R., Neumann, J., Dunay, I.R., Dityatev, A. Glia (2020). https://doi.org/10.1002/glia.23894

Interplay between perivascular and perineuronal extracellular matrix remodelling in neurological and psychiatric diseases. Ulbrich, P., Khoshneviszadeh, M., Jandke, S., Schreiber, S., Dityatev, A. European Journal of Neuroscience (2020). https://doi.org/10.1111/ejn.14887

Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Bayraktar, G., Yuanxiang, P., Confettura, A.D., Gomes, G.M., Raza, S.A., Stork, O., Tajima, S., Suetake, I., Karpova, A., Yildirim, F., Kreutz, M.R. Neuropsychopharmacol. (2020). https://doi.org/10.1038/s41386-020-0780-2

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences. K.Y. Liu, R.A. Kievit, K.A. Tsvetanov, M.J. Betts, E.Duzel, J.B. Rowe, C.A.N. Cam, R. Howard, D. Hammerer. Nat Commun. 2020 Apr 11(1), 1712; https://doi.org/10.1038/s41467-020-15410-w

2019

Locus coeruleus MRI contrast is reduced in Alzheimer’s disease dementia and correlates with CSF Abeta levels. M.J. Betts, A. Cardenas-Blanco, M. Kanowski, A. Spottke, S.J. Teipel, I. Kilimann, F. Jessen, E.Duzel. Alzheimers Dement. 2019 Dec 281-285; https://doi.org/10.1016/j.dadm.2019.02.001

Epigenetic mechanism of carbohydrate sulfotransferase 3 (CHST3) downregulation in the aging brain. Baidoe-Ansah D., Sakib M.S., Jia S., Fischer A., Kaushik R.Dityatev A. bioRxiv 741355; https://doi.org/10.1101/741355