2021
Influenza A Virus (H1N1) Infection Induces Microglial Activation and Temporal Dysbalance in Glutamatergic Synaptic Transmission. Düsedau H.P., Steffen J., Figueiredo C.A., Boehme J.D., Schultz K., Erck C., Korte M., Faber-Zuschratter H., Smalla K.H., Dieterich D., Kröger A., Bruder D., Dunay IR.mBio. 2021 Oct 26;12(5):e0177621. https://doi.org/10.1128/mBio.01776-21
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R. Dankovich T.M., Kaushik R., Olsthoorn L.H.M., Petersen G.C., Giro P.E., Kluever V., Agüi-Gonzalez P., Grewe K., Bao G., Beuermann S., Hadi H.A., Doeren J., Klöppner S., Cooper B.H., Dityatev A., Rizzoli S.O. Nat Commun. 2021 Dec 8;12(1):7129. https://doi.org/10.1038/s41467-021-27462-7
Antibiotic-induced gut dysbiosis leads to activation of microglia and impairment of cholinergic gamma oscillations in the hippocampus. Çalışkan G., French T., Enrile Lacalle S., Del Angel M., Steffen J., Heimesaat MM., Rita Dunay I., Stork O. (2021) Brain, Behavior, and Immunity 99:203-217. https://doi.org/10.1016/j.bbi.2021.10.007
Brain extracellular matrix: An upcoming target in neurological and psychiatric disorders. Dityatev A., Seidenbecher C. and Morawski, M. (2021) Eur J Neurosci 2021 53: 3807-3810. https://doi.org/10.1111/ejn.15336
CSF and PET biomarkers for noradrenergic dysfunction in neurodegenerative diseases: a systematic review and meta-analysis. Lancini E., Haag L., Bartl F., Rühling M., Ashton N.J., Zetterberg H., Düzel E., Hämmerer D., Betts M.J. https://doi.org/10.1101/2021.09.30.21264271
Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice. Strackeljan L., Baczynska E., Cangalaya C., Baidoe-Ansah D., Wlodarczyk, J.; Kaushik R., Dityatev A. Cells2021, 10, 1862. https://doi.org/10.3390/cells10081862
Transgenic modelling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function. Madencioglu D.A., Çalışkan G., Yuanxiang P., Rehberg K., Demiray Y.E., Kul E., Engler A., Hayani H., Bergado-Acosta J.R., Kummer A., Müller I., Song I., Dityatev A., Kähne T., Kreutz M.R., Stork O. iScience in press, 2021. https://doi.org/10.1016/j.isci.2021.102868
The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling. Annamneedi A., del Angel C.M., Gundelfinger E.D., Stork O., Caliskan G.. International Journal of Molecular Sciences 22(15):7944. 2021. https://doi.org/10.3390/ijms22157944
Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses. Bucher M., Niebling S., Han Y., Molodenskiy D., Hassani Nia F., Kreienkamp H.J., Svergun D., Kim E., Kostyukova A.S., Kreutz M.R., Mikhaylova M. Elife. 202110:e66165. https://doi.org/10.7554/eLife.66165
Met carriers of the BDNF Val66Met polymorphism show reduced Glx/NAA in the pregenual ACC in two independent cohorts. Martens, L., Herrmann, L., Colic, L., Li, M., Richter, A., Behnisch, G., Stork, O., Seidenbecher, C., Schott, B.H., Walter, M. Sci Rep. 2021 Mar 24;11(1):6742. https://doi.org/10.1038/s41598-021-86220-3
To err is (not only) human: Mechanisms of post-error attentional regulation illuminated in mice. Ullsperger, M., Stork, O. Neuron 109(7):1074-1076. 2021 https://doi.org/10.1016/j.neuron.2021.03.014
Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats. Derbis M, Kul E, Niewiadomska, D., Sekrecki, M., Piasecka, A., Taylor, K., Hukema, R.K., Stork, O., Sobczak, K. Nat Commun. 2021 Feb 24;12(1):1265.PMID: 33627639 https://doi.org/10.1038/s41467-021-21021-w
The nuclear lamina is a hub for the nuclear function of Jacob. Samer, S., Raman, R., Laube, G., Kreutz, M.R., Karpova, A.Mol Brain. 2021 14(1):9. https://doi.org/10.1186/s13041-020-00722-1
2020
Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis. Stoyanov, S., Sun, W., Düsedau, H.P., Cangalaya, C., Choi, I., Mirzapourdelavar, H., Baidoe‐Ansah, D., Kaushik, R., Neumann, J., Dunay, I.R., Dityatev, A. Glia (2020). https://doi.org/10.1002/glia.23894
Interplay between perivascular and perineuronal extracellular matrix remodelling in neurological and psychiatric diseases. Ulbrich, P., Khoshneviszadeh, M., Jandke, S., Schreiber, S., Dityatev, A. European Journal of Neuroscience (2020). https://doi.org/10.1111/ejn.14887
Synaptic control of DNA methylation involves activity-dependent degradation of DNMT3A1 in the nucleus. Bayraktar, G., Yuanxiang, P., Confettura, A.D., Gomes, G.M., Raza, S.A., Stork, O., Tajima, S., Suetake, I., Karpova, A., Yildirim, F., Kreutz, M.R. Neuropsychopharmacol. (2020). https://doi.org/10.1038/s41386-020-0780-2
2019
Epigenetic mechanism of carbohydrate sulfotransferase 3 (CHST3) downregulation in the aging brain. Baidoe-Ansah D., Sakib M.S., Jia S., Fischer A., Kaushik R., Dityatev A. bioRxiv 741355; https://doi.org/10.1101/741355