Our steering committee consists of our spokesperson, our vice-spokesperson, 2 PIs, our coordinator, a student´s ombudsperson (PI or postdoc, elected by our students) and 2 student representatives (1 PhD and 1 MD student). The members of the steering committee are committed to report to the DFG, mediate in case of conflicts, coordinate public outreach, manage all administrative hurdles and organize the educational program.
Prof. Dr. Daniela Dieterich
Speaker RTG2413 & Director of the Institute for Pharmacology and Toxicology, Medical Faculty, OVGU,PI of Neural Plasticity and Communication
The work in my lab concentrates on the molecular and cellular underpinnings of protein homeostasis at the multipartite synapse and their consequences for brain function during aging. My major goals within the graduate program SynAGE is to guide young scientists along their ways to develop their very own line of research, to support the intersection of ideas across disciplines, and thereby to catalyze discovery.
Prof. Dr. Oliver Stork
Head of the Department of Genetics and Molecular Neurobiology, Institute of Biology, OVGU
My work is devoted to the understanding of molecular mechanisms that mediate information processing in the brain and the control of behavior. In my group we are particularly interested in long-term change in GABAergic interneurons that control local circuit activity as well as extended network activity patterns in the limbic brain system. Our focus lies on unraveling the intracellular pathways controlling homeostatic plasticity in both GABAergic and their excitatory target neurons. We address the role of these cells with molecular and physiological tools in cell culture, genetically manipulated mice and following acut viral interventions.
Prof. Dr. Constanze Seidenbecher
Committee member, LIN
I am a group leader at the Leibniz Institute for Neurobiology (LIN) Magdeburg. My scientific interests are devoted to synaptic molecules and the brain extracellular matrix and their role in neuroplasticity and cognitive functions.
I am member of the Board of directors of the Center for Behavioral Brain Sciences (CBBS) Magdeburg, steering committee member of the SFB „Neurobiology of motivated behavior“ and deputy speaker of the graduate school ABINEP. In 2019 I was elected as council member of the International Society for Neurochemistry (ISN).
My aim is to further support excellent young scientists – with a special focus on female researchers – by connecting, inspiring and promoting young careers in SynAGE and beyond.
Dr. Michael R. Kreutz
Committee member, LIN
My research in NPlast in Magdeburg and DOF in Hamburg is concerned with fundamental questions on how synapses communicate with the nucleus, how gene activity-dependent gene expression feeds back to synaptic function and how this is related to the formation of a cellular engram and last but not least how the nanoscale organization of the synapse determines functional properties in the context of learning and memory. We use a multi-disciplinary approach with studies ranging from single molecules to in vivo animal experimentation. We also address translational aspects where we try to understand whether the processes that we investigate might be relevant for disease. The Leibniz Group ‚Dendritic Organelles and Synaptic Function‘ at the ZMNH in Hamburg investigates how microsecretory systems and organelles in neurites are involved in synaptic function. We are interested in organelles like autophagosomes, lysosomes, and Golgi satellites and their local contribution to neurotransmission.
Dr. Anika Dirks
Coordination of RTG 2413 SynAGE
After studying Biochemistry at the Martin Luther University Halle, I did my PhD in Molecularbiology and Neurochemistry at the Leibniz Institute for Neurobiologie Magdeburg. During that time, my life focused on the presynapse-to-nucleus shuttling protein CtBP1.
Since 2017, I have worked as scientific coordinator at LIN and OVGU, especially at the center for behavioral brain sciences cbbs and the cbbs graduate program. I like to help young motivated students to complete their MD or PhD, which I am looking forward to continue and intensify at SynAGE.
Dr. Anne Albrecht
Postdoc at the Department of Genetics and Molecular Neurobiology, Institute of Biology, OVGU & Ombudsperson SynAGE
My work aims for understanding neuronal mechanisms of stress resilience and vulnerability. Usually individuals cope well with aversive experiences, but if they become too intense or last too long, stress-induced neuropsychopathologies such as anxiety disorders or depression can occur. Using different models of stress in juvenile and adult rodents, we study how stress across the life span affects anxiety, learning and memory. Specifically we are interested on how such stress experiences shape local GABAergic interneuron circuits, signaling by modulatory neuropeptides as well as astrocyte-neuron-interactions in the dorsal and ventral hippocampus. To that end, we utilize biochemical and molecular tools such as high-resolution gene expression analysis with laser microdissection and quantitative PCR and combine it with testing emotional and cognitive functions in transgenic mice and after acute pharmacological and viral interventions.
PhD Student Project 1, SynAGE Student Board Member
My work concentrates on the protein homeostasis in the aging brain. Specifically I am interested in processes that lead to an altered protein expression and autophagy in the aged brain. Furthermore I want to determine the interaction and effect of anti-inflammatory and antidiabetic strategies to rejuvenate autophagy and neural protein homeostasis.